Autophagy Is Involved in Mesenchymal Stem Cell Death in Coculture with Chondrocytes.
Carlo Alberto PaggiAmel DudakovicYao FuCatalina Galeano GarcesMario HevesiDaniela Galeano GarcesAllan B DietzChristopher R ParadiseMarcel KarperienPublished in: Cartilage (2020)
In cocultures of human MSCs with primary chondrocytes, autophagy is involved in the disappearance of MSCs. We propose that this sacrificial cell death may contribute to the trophic effects of MSCs on cartilage formation.