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The release of host-derived antibodies bound to the variant surface glycoprotein (VSG) of Trypanosoma brucei cannot be explained by pH-dependent conformational changes of the VSG dimer.

Patrick EirichPavel NesterovSergey ShityakovEkaterina V SkorbBodo SanderJens BroscheitThomas DandekarNicola G JonesMarkus Engstler
Published in: Open research Europe (2024)
Thus, the dissociation of anti-VSG-antibodies in endosomes cannot be explained by changes in pH.
Keyphrases
  • molecular dynamics
  • molecular dynamics simulations