Gender specific decrease of a set of circulating N-acylphosphatidyl ethanolamines (NAPEs) in the plasma of Parkinson's disease patients.
Zeeshan HamidAbdul BasitSilvia PontisFabrizio PirasFrancesca AssognaPaola BossùFrancesco Ernesto PontieriAlessandro StefaniGianfranco SpallettaPietro FranceschiAngelo ReggianiAndrea ArmirottiPublished in: Metabolomics : Official journal of the Metabolomic Society (2019)
In the current study we have shown the downregulation of NAPEs in plasma of PD patients and we thus speculate that these lipids might serve as candidate biomarkers for PD. We also suggest a molecular mechanism, explaining our findings, which involves gut microbiota.