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Association of Suppressive Myeloid Cell Enrichment with Aggressive Oropharynx Squamous Cell Carcinoma.

Changlin YangRekha GargKristanna FredenburgFrances WeidertHector Mendez-GomezRobert AmdurJi-Hyun LeeJamie KuJesse KresakStephanie A S StarasAndrew G SikoraLily WangDaniel McGrailDuane MitchellElias SayourNatalie Silver
Published in: Cancers (2023)
our study demonstrates that patients with recurrent HPV+ OPSCC had suppressive monocyte/macrophage and granulocyte immune-cell enrichment, similar to those seen in the more aggressive HPV-negative OPSCC.
Keyphrases
  • squamous cell carcinoma
  • dendritic cells
  • high grade
  • peripheral blood
  • single cell
  • adipose tissue
  • bone marrow
  • immune response
  • cell therapy
  • lymph node metastasis
  • cervical cancer screening