Fluoroalkyl sulfides as photoredox-active coupling reagents for alkene difunctionalization.
Mikhail D KosobokovMikhail O ZubkovVitalij V LevinVladimir A KokorekinAlexander D DilmanPublished in: Chemical communications (Cambridge, England) (2021)
A visible-light-promoted fluoroalkylation-thiolation of alkenes is described. A 4-tetrafluoropyridinylthio fragment serves as a photoredox-active group in the initiation step and undergoes a radical group transfer, which is important for the reaction efficiency. In the primary products, the pyridinylthio substituent may be further functionalized via radical processes or an aromatic substitution reaction.