The excess insulin requirement in severe COVID-19 compared to non-COVID-19 viral pneumonitis is related to the severity of respiratory failure and pre-existing diabetes.

Sam M LockhartHarry GriffithsBogdan PetrisorAmmara UsmanJulia Calvo-LatorreLaura HealesVishakha BansiyaRazeen MahroofAndrew Conway Morris

Published in: Endocrinology, diabetes & metabolism (2021)

In this single-centre study, we could not find evidence of a unique diabetogenic effect of COVID-19. We suggest that high insulin requirements in this disease relate to its propensity to cause severe respiratory failure in patients with pre-existing metabolic disease.

Keyphrases

respiratory failure
sars cov
coronavirus disease
type diabetes
extracorporeal membrane oxygenation
mechanical ventilation
glycemic control
respiratory syndrome coronavirus
early onset
acute respiratory distress syndrome
cardiovascular disease
intensive care unit
insulin resistance
metabolic syndrome