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Falsely normal CT perfusion ischemic core readings are common and often associated with deep infarcts.

Mehdi BouslamaKrishnan RavindranGabriel Martins RodriguesLeonardo PisaniDiogo C HaussenMichael R FrankelRaul G Nogueira
Published in: Journal of neurointerventional surgery (2022)
CTP may completely fail to detect ischemic core in as many as 25% of cases, especially in isolated deep MCA strokes. Technical refinements of the post-processing algorithms are therefore warranted. TMC infarcts may have a lower risk of reperfusion hemorrhage, potentially due to greater preservation of the neurovascular unit structure in face of delayed recovery of cerebral blood flow.
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