Effects of Ketamine Infusion on Breathing and Encephalography in Spontaneously Breathing ICU Patients.
Aiman SuleimanPeter SanterRonny Munoz-AcunaMaximilian HammerMaximilian S SchaeferLuca J WachtendorfSandra RumyantsevLorenzo BerraShubham ChamadiaOluwaseun Johnson-AkejuElias N Baedorf-KassisMatthias EikermannPublished in: Journal of intensive care medicine (2022)
In intubated, spontaneously breathing patients receiving a constant rate of propofol, ketamine increased inspiratory flow, reduced inspiratory work of breathing, and was associated with an "activated" electroencephalographic pattern. These characteristics might facilitate weaning from mechanical ventilation.