Urinary miR-155-5p and CXCL10 as prognostic and predictive biomarkers of rejection, graft outcome and treatment response in kidney transplantation.

Olga MillánKlemens BuddeClaudia SommererIrene AliartOlesja RisslingBeatriz BardajiMaaren MatzMartin ZeierIrene SilvaLluis GuiradoMercè Brunet

Published in: British journal of clinical pharmacology (2017)

The regular early post-transplantation monitoring of urinary miR-155-5p and CXCL10 can help in the prognosis of AR and graft dysfunction. Large prospective randomized multicentre trials are warranted to refine our cut-off values and validate the clinical usefulness of these biomarkers.

Keyphrases

kidney transplantation
double blind
placebo controlled
clinical trial
open label
oxidative stress
study protocol
phase iii
phase ii
stem cells