Biomedical Applications of Iron Oxide Nanoparticles: Current Insights Progress and Perspectives.
María Gabriela Montiel SchneiderMaría Julia MartínJessica OtarolaEkaterina VakarelskaVasil D SimeonovVerónica LassalleMiroslava A NedyalkovaPublished in: Pharmaceutics (2022)
The enormous development of nanomaterials technology and the immediate response of many areas of science, research, and practice to their possible application has led to the publication of thousands of scientific papers, books, and reports. This vast amount of information requires careful classification and order, especially for specifically targeted practical needs. Therefore, the present review aims to summarize to some extent the role of iron oxide nanoparticles in biomedical research. Summarizing the fundamental properties of the magnetic iron oxide nanoparticles, the review's next focus was to classify research studies related to applying these particles for cancer diagnostics and therapy (similar to photothermal therapy, hyperthermia), in nano theranostics, multimodal therapy. Special attention is paid to research studies dealing with the opportunities of combining different nanomaterials to achieve optimal systems for biomedical application. In this regard, original data about the synthesis and characterization of nanolipidic magnetic hybrid systems are included as an example. The last section of the review is dedicated to the capacities of magnetite-based magnetic nanoparticles for the management of oncological diseases.
Keyphrases
- iron oxide nanoparticles
- magnetic nanoparticles
- machine learning
- primary care
- public health
- molecularly imprinted
- prostate cancer
- working memory
- radical prostatectomy
- young adults
- rectal cancer
- pain management
- chronic pain
- health information
- cell therapy
- smoking cessation
- childhood cancer
- drug induced
- minimally invasive