Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries.
Miren García-CortésAida Ortega-AlonsoGonzalo Matilla-CabelloInmaculada Medina-CalizAgustín CastiellaIsabel CondeElvira BonillaJose M Pinazo-BanderaNelia HernándezMartin TagleVinícius Santos NunesRaymundo ParanáFernando BessoneNeil KaplowitzMaría Isabel LucenaIsmael Alvarez-AlvarezMercedes Robles-DiazRaúl Jesús AndradePublished in: Liver international : official journal of the International Association for the Study of the Liver (2023)
DILI with autoimmune features shows different clinical features than DILI patients lacking characteristics of autoimmunity. Higher transaminases and total bilirubin values with no eosinophilia at presentation increase the likelihood of relapse in DILI with autoimmune features. As the tendency to relapse increases over time, these patients will require long-term follow-up.