Relationships of Self-reported Opioid Use and Misuse and Pain Severity With Probable Major Depression Among Participants With Spinal Cord Injury.
James S KrauseClara E Dismuke-GreerNicole D DiPiroJillian M R ClarkJon Laursen-RoeslerPublished in: Archives of physical medicine and rehabilitation (2024)
The relation between pain intensity with depressive symptom severity and PMD was profound, consistent with the biopsychosocial model of pain. The greater risk of PMD and higher depressive symptom severity among those using opioids and misusing opioids raises further concern about long-term prescription opioid use. Alternative treatments are needed.