Diffusosides C and D, two new iridoid glucosides from Oldenlandia diffusa.

Published in: Natural product research (2020)

During our continual investigations on Oldenlandia diffusa (Willd.) Roxb., two new iridoid glucosides, diffusosides C (1) and D (2), were isolated and their structures were elucidated through cumulative analysis of NMR and HRESIMS spectroscopic data as well as computational studies. Both isolated compounds displayed no obvious neuroprotective activity on H2O2-induced injury PC12 cells at 50 μM in vitro.

Keyphrases

high resolution
magnetic resonance
molecular docking
high glucose
electronic health record
case control
cerebral ischemia
oxidative stress
data analysis
subarachnoid hemorrhage