Identification of distinct phenotypes related to benralizumab responsiveness in patients with severe eosinophilic asthma.

Hideyasu YamadaMasayuki NakajimaMasashi MatsuyamaYuko MorishimaNaoki AraiNorihito HidaTaisuke NakaizumiHironori MasukoYohei YatagaiTakefumi SaitoNobuyuki Hizawa

Published in: PloS one (2021)

This study, to the best of our knowledge, is the first cluster analysis to report distinct phenotypes related to clinical benralizumab response in a real-world population with severe eosinophilic asthma. These results may help to predict responsiveness to benralizumab in patients with severe eosinophilic asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
early onset
allergic rhinitis
chronic rhinosinusitis
drug induced
air pollution
cystic fibrosis