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Use of letermovir for cytomegalovirus primary prophylaxis in lung transplant recipients.

Hanna L KleiboekerJacob WangNicole BorkowskiBrad MinerAlyson PromKrista PaplaczykJennifer WrightMrinalini Venkata SubramaniAmbalavanan ArunachalamAlan D BetensleyRade TomicCatherine N Myers
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2024)
In this single-center study, the incidence of leukopenia and neutropenia requiring GCSF were reduced with LTV compared to VGC. Breakthrough and post-PPX infections were not significantly different. This evidence suggests that LTV has comparable efficacy with reduced myelosuppression compared to VGC in LTX recipients, and may be an appropriate alternative for PPX.
Keyphrases
  • risk factors
  • epstein barr virus
  • kidney transplantation
  • diffuse large b cell lymphoma