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Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation.

Lance T DenesLance A RileyJoseph R MijaresJuan D ArboledaKendra McKeeKaryn A EsserEric T Wang
Published in: Skeletal muscle (2019)
Our results suggest that growing C2C12 myotubes on micropatterned gelatin hydrogels accelerates sarcomere formation and yields a more fully matured myotube culture. Thus, the use of micropatterned hydrogels is a viable and simple approach to better model skeletal muscle biology in vitro.
Keyphrases
  • hyaluronic acid
  • tissue engineering
  • skeletal muscle
  • drug delivery
  • drug release
  • extracellular matrix
  • wound healing
  • metabolic syndrome
  • type diabetes