Dual therapy with oral anticoagulation and single antiplatelet agent versus monotherapy with oral anticoagulation alone in patients with atrial fibrillation and stable ischemic heart disease: a systematic review and meta-analysis.
Aamina ShakirArsalan KhanSiddharth AgarwalShari CliftonJessica ReeseMuhammad Bilal MunirUsama Bin NasirSafi U KhanRakesh GopinathannairChristopher V DeSimoneAbhishek DeshmukhWarren M JackmanStavros StavrakisZain Ul Abideen AsadPublished in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2022)
In patients with AF and stable ischemic heart disease, OAC + SAPT as compared to OAC monotherapy is associated with a significant increase in bleeding events without a significant reduction in thrombotic events, cardiovascular mortality, and all-cause mortality.