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Integrative analysis of lung molecular signatures reveals key drivers of systemic sclerosis-associated interstitial lung disease.

Seung-Min JungKyung-Su ParkKi-Jo Kim
Published in: Annals of the rheumatic diseases (2021)
Integrative transcriptomic analysis of lung tissues revealed key signatures of fibrosis in SSc-ILD. A network-based Bayesian approach provides deep insights into key regulatory genes and molecular targets applicable to treating SSc-ILD.
Keyphrases
  • interstitial lung disease
  • systemic sclerosis
  • genome wide
  • rheumatoid arthritis
  • idiopathic pulmonary fibrosis
  • network analysis
  • gene expression
  • transcription factor
  • dna methylation
  • genome wide identification