Polyethylene glycol-coated porous magnetic nanoparticles for targeted delivery of chemotherapeutics under magnetic hyperthermia condition.

Ali Dabbagh Ziba Hedayatnasab Hamed KarimianMasoud SarrafChai Hong Yeong Hamid Reza Madaah Hosseini Noor Hayaty Abu Kasim Tin-Wui Wong Noorsaadah Abdul Rahman

Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2018)

The large pores generated in the PMNPs structure could provide a sufficient space for encapsulation of the chemotherapeutics as well as fast drug encapsulation and release kinetics, which together with thermosensitive characteristics of the PEG1500 shell, make DOX-PEG1500-PMNPs promising adjuvants to the magnetic hyperthermia modality.

Keyphrases

adverse drug
magnetic nanoparticles
molecularly imprinted
drug delivery
emergency department
metal organic framework
solid phase extraction
mass spectrometry