Impact of Biomarker-based Design Strategies on the Risk of False-Positive Findings in Targeted Therapy Evaluation.
Tat-Thang VoAlexandre VivotRaphael PorcherPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
The drug-biomarker coevaluation based on a series of independent enrichment trials can result in a high risk of false-positive findings. CVASD with some appropriate adjustments can be a good alternative to overcome this multiplicity issue.
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