Investigation of correlations between DNA methylation, suicidal behavior and aging.
Richie JeremianYi-An ChenVincenzo De LucaJohn B VincentJames L KennedyClement C ZaiJohn StraussPublished in: Bipolar disorders (2017)
We report significant findings at three loci based on a methylome scan of participants with BD for an SB phenotype, and potentially altered molecular aging in suicide attempters. Despite the small sample size, our proof-of-concept study highlights the potential for epigenetic factors to be useful in understanding the molecular underpinnings of suicide with the ultimate aim of its prevention.