M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms.

Sameh LotfiHesham NasserOsamu NoyoriMasateru HiyoshiHiroaki TakeuchiYoshio KoyanagiShinya Suzu

Published in: Retrovirology (2020)

By taking advantage of useful features of U87 cells, we provided evidence that M-Sec mediates a rapid and efficient cell-cell transmission of HIV-1 at an early phase of infection by enhancing both TNT formation and cell motility.

Keyphrases

single cell
antiretroviral therapy
cell therapy
hiv positive
hiv testing
human immunodeficiency virus
induced apoptosis
hiv aids
stem cells
men who have sex with men
escherichia coli
signaling pathway
cell death
quantum dots