In the midst of a dangerous intersection with unclear therapeutic strategies: a challenging case of severe aortic stenosis.
Guglielmo GalloneFederico LandraFabrizio D'AscenzoFederico ConrottoRoberta CasoniFrancesco BrunoPierluigi OmedèGianluca AlunniAlessandro AndreisAlessandro VairoMauro GiorgiAntonella FavaGaetano Maria De FerrariPublished in: BMC cardiovascular disorders (2020)
In the presented case, we deemed the natural history of ATTR-CA amyloidosis to negatively affect both the patient' prognosis and procedural risk, adversing TAVR indication despite symptomatic severe AS. No clear evidence is currently available to guide decision making in this setting, advocating for prospective studies to clarify if TAVR may have a prognostic benefit in ATTR-CA - and which ATTR-CA - patients.
Keyphrases
- aortic stenosis
- ejection fraction
- transcatheter aortic valve replacement
- aortic valve
- aortic valve replacement
- transcatheter aortic valve implantation
- left ventricular
- end stage renal disease
- early onset
- chronic kidney disease
- coronary artery disease
- newly diagnosed
- protein kinase
- prognostic factors
- peritoneal dialysis
- atrial fibrillation