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Differences in the Oral Microbiome in Patients With Early Rheumatoid Arthritis and Individuals at Risk of Rheumatoid Arthritis Compared to Healthy Individuals.

Johanna Margaretha KroeseBernd W BrandtMark J BuijsWim CrielaardLobbezoo FrankBruno G LoosLaurette van BoheemenDirkjan van SchaardenburgEgija ZauraC M C Catherine Volgenant
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
The results show similarities in the oral microbiome between patients with early RA and at-risk individuals, since in both groups, the oral microbiome was characterized by an increased relative abundance of potentially proinflammatory species when compared to that in healthy controls. These findings suggest a possible association between the oral microbiome and the onset of RA.
Keyphrases
  • rheumatoid arthritis
  • disease activity
  • ankylosing spondylitis
  • interstitial lung disease
  • wastewater treatment