Rapid Base-Specific Calling of SARS-CoV-2 Variants of Concern Using Combined RT-PCR Melting Curve Screening and SIRPH Technology.

Sascha TierlingKathrin KattlerMarkus VogelgesangThorsten PfuhlStefan LohseChristina Lo PortoBeate SchmittSeiwert NastasjaAbdulrahman SalhabSigrun SmolaJörn Walter

Published in: Open forum infectious diseases (2021)

We applied the sensitive method to monitor local variant of concern outbreaks in SARS-CoV-2-positive samples collected in a confined region of Germany.

Keyphrases

sars cov
respiratory syndrome coronavirus
high resolution
copy number
loop mediated isothermal amplification
genome wide
sensitive detection