Family environment and polygenic risk in the bipolar high-risk context.

Emma K StappJanice M FullertonRashelle J MusciPeter P ZandiMelvin G McInnisPhilip B MitchellLeslie A HulvershornNeera GhaziuddinGloria RobertsAlessandra G FerreraJohn I NurnbergerHolly C Wilcox

Published in: JCPP advances (2023)

The data suggest that the relationship of BD-PRS and offspring liability for BD differed between well-functioning versus high-conflict FE, potentially in line with a multifactorial liability threshold model and supporting future study of and interventions improving family dynamics.

Keyphrases

high fat diet
bipolar disorder
physical activity
electronic health record
current status
type diabetes
skeletal muscle
data analysis