Transient receptor potential ankyrin 1 agonists improve intestinal transit in a murine model of postoperative ileus.
K TsuchiyaK KubotaK OhbuchiA KanekoN OhnoA MaseH MatsushimaMasahiro YamamotoK MiyanoY UezonoT KonoPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2016)
Intraluminal TRPA1 stimulation is a potential therapeutic strategy for GI motility disorders. Further investigation is required to determine whether 5-HT and/or ECC are involved in the effect of TRPA1 on motility.