Longitudinal strain is an independent predictor of survival and response to therapy in patients with systemic AL amyloidosis.
Oliver C CohenAndreia IsmaelBabita PawarovaRicha ManwaniSriram RavichandranSteven LawDarren FoardAviva PetrieSevda WardBrooke DouglasAna Martinez-NaharroLiza ChackoCandida Cristina QuartaShameem MahmoodSajitha SachchithananthamHelen J LachmannPhilip N HawkinsJulian David GillmoreMarianna FontanaRodney H FalkCarol J WhelanAshutosh D WechalekarPublished in: European heart journal (2021)
Baseline LS% is a functional marker that correlates with worsening cardiac involvement and is predictive of survival. Baseline LS% and an absolute improvement in LS% are useful additional measures of prognosis and response to therapy in cardiac AL amyloidosis, respectively.