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In Vitro Inflammatory Cell-Induced Corrosion Using a Lymphocyte and Macrophage Coculture.

Madison N BrownLisa H PhanDanielle M BryantRichard A SmithBrian R MorrowWilliam M Mihalko
Published in: The Journal of arthroplasty (2024)
This study demonstrates the ability of macrophages to alter the surface chemistry of commonly used orthopaedic alloys. We found that the addition of lymphocytes and a simulated local inflammatory response may contribute to the ICIC of CoCrMo implants.
Keyphrases
  • inflammatory response
  • peripheral blood
  • single cell
  • oxidative stress
  • diabetic rats
  • cell therapy
  • immune response
  • toll like receptor
  • mesenchymal stem cells
  • bone marrow
  • endothelial cells
  • stress induced