A prospective observational cohort study comparing the treatment effectiveness and safety of ciclosporin, dupilumab and methotrexate in adult and paediatric patients with atopic dermatitis: results from the UK-Irish A-STAR register.

Helen AlexanderRayka MalekDavid Prieto-MerinoElizaveta GribalevaManisha BadenPaula BeattieSara BrownTim BurtonShona CameronBola CokerMichael J CorkRoss HearnJohn R IngramAlan D IrvineGraham A JohnstonAlice LambertMark LuntIrene ManLouise NewellGraham OggPrakash PatelMandy WanRichard Bruce WarrenRichard WoolfZenas Zee Ngai YiuNick ReynoldsMichael R Ardern-Jones Carsten Flohrnull null

Published in: The British journal of dermatology (2024)

This real-world comparison of CyA, dupilumab and MTX in AD suggests that dupilumab is consistently more effective than MTX and that CyA is most effective in very severe disease within one follow-up year.

Keyphrases

atopic dermatitis
intensive care unit
emergency department
high dose
early onset
general practice
primary care
low dose
young adults