Genetic predisposition to type 2 diabetes is associated with severity of coronary artery disease in patients with acute coronary syndromes.
Qiwen ZhengJie JiangYong HuoDafang ChenPublished in: Cardiovascular diabetology (2019)
Our data indicated that genetic predisposition to T2D is associated with elevated risk of severe CAD. This association revealed a possible causal relationship and is partially mediated through diabetic status.
Keyphrases
- coronary artery disease
- type diabetes
- acute coronary syndrome
- percutaneous coronary intervention
- genome wide
- copy number
- cardiovascular events
- coronary artery bypass grafting
- glycemic control
- electronic health record
- insulin resistance
- antiplatelet therapy
- early onset
- big data
- metabolic syndrome
- wound healing
- adipose tissue
- left ventricular
- machine learning
- data analysis
- ejection fraction