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EAAT1-dependent slc1a3 Transcriptional Control depends on the Substrate Translocation Process.

Dinorah Hernández-MelchorLeticia Ramírez-MartínezLuis CidCecilia Palafox-GómezEsther López-BayghenArturo Ortega
Published in: ASN neuro (2022)
EAAT1/GLAST down-regulates its expression and function at the transcriptional level by activating a signaling pathway that includes PI3K, PKC and NF-κB, favoring the notion of an activity-dependent fine-tuning of glutamate recycling and its synaptic transactions through glial cells.
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