A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1.
Dengqiu XuLei ZhaoJingwei JiangSijia LiZeren SunXiaofei HuangChunjie LiTao WangLixin SunXihua LiZhen-Zhou JiangLuyong ZhangPublished in: Journal of cachexia, sarcopenia and muscle (2020)
Our findings show that catalpol and TAK1 inhibitors substantially improve whole-body muscle health and the function of dystrophic skeletal muscles and may provide a novel therapy for DMD.