C3 Glomerulopathy Recurs Early after Kidney Transplantation in Serial Biopsies Performed within the First 2 Years after Transplantation.
Blanca TarragónYonatan PelegGeetha JagannathanMiroslav SekulicJae-Hyung ChangDavid J CohenRussell J CrewGeoffrey K DubeHilda E FernandezRadica Z AlicicSumit MohanHeather K MorrisGerald B AppelParesh JadavDominick SantorielloSatoru KudoseMichael B StokesIbrahim BatalAndrew S BombackPublished in: Clinical journal of the American Society of Nephrology : CJASN (2024)
Most of the patients with native kidney failure attributed to C3G developed disease recurrence very early after kidney transplantation, usually with minimal proteinuria, mild histologic alterations, and favorable short-term allograft survival. Immunofluorescence and electron microscopy played a crucial role in detecting early, subclinical recurrence of C3GN and DDD, which showed significant overlapping features.