Reflex Human Immunodeficiency Virus (HIV) Type 1 RNA Testing Enables Timely Differentiation of False-Positive Results From Acute HIV Infection.
Christopher KaperakDylan EllerSamantha A DevlinAndré HallJessica SchmittEleanor E FriedmanKathleen G BeavisKimberly A StanfordDavid PitrakMoira C McNultyPublished in: Open forum infectious diseases (2023)
Accurate, timely human immunodeficiency virus (HIV) diagnosis is critical. Routine HIV screening program data were examined before and after reflex HIV type 1 RNA testing. Reflex testing facilitated confirmation of reactive HIV screening assays (as true or false positives) (odds ratio, 23.7 [95% confidence interval, 6.7-83.4]; P < .0001), improving detection of acute HIV and reducing unconfirmed discordant results.
Keyphrases
- human immunodeficiency virus
- antiretroviral therapy
- hiv infected
- hiv positive
- hepatitis c virus
- hiv aids
- hiv testing
- men who have sex with men
- south africa
- machine learning
- acute respiratory distress syndrome
- artificial intelligence
- intensive care unit
- respiratory failure
- high throughput
- sensitive detection
- data analysis
- clinical practice