Scalp ripples as prognostic biomarkers of epileptogenicity in pediatric surgery.
Eleonora TamiliaMatilde DirodiMichel AlhilaniP Ellen GrantJoseph R MadsenSteven M StufflebeamPhillip L PearlChristos PapadelisPublished in: Annals of clinical and translational neurology (2020)
HD-EEG and MEG localize interictal ripples with high precision in children with refractory epilepsy. Scalp ripples-on-spikes are prognostic, noninvasive biomarkers of epileptogenicity, since removing their cortical generators predicts good outcome. Conversely, scalp ripples-alone are most likely generated by non-epileptogenic areas.