Clinical Safety and Narcolepsy-like Symptoms of Dual Orexin Receptor Antagonists in Patients with Insomnia: A Systematic Review and Meta-Analysis.

This meta-analysis achieved a comparative evaluation of the clinical safety and tolerability of FDA-approved DORAs for primary insomnia, specifically focusing on AEs-related narcolepsy-like symptoms. This study contributes to understanding the safety profile of FDA-approved DORAs for treating insomnia.