Does Timing of Ileal Pouch-Anal Anastomosis Matter in Patients With Primary Sclerosing Cholangitis and Orthotopic Liver Transplantation? A Systematic Review and Meta-analysis.

Saqr AlsakarnehMohamed AhmedFouad JaberMir ZulqarnainRaffi KaragozianFadi FrancisFrancis A Farraye Jana G Hashash

Published in: Crohn's & colitis 360 (2024)

Our meta-analysis revelaed that pouchitis is common in patients who underwent OLT for PSC, especially in those who had IPAA before the OLT. OLT before IPAA may reduce the risk of pouchitis. Further larger studies are warranted to reproduce this and investigate the reason behind this difference.

Keyphrases

systematic review
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
case control
high grade
meta analyses
patient reported outcomes