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Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis.

Kosuke MinagaTomohiro WatanabeYasuyuki AraiMasahiro ShiokawaAkane HaraTomoe YoshikawaKen KamataKouhei YamashitaMasatoshi Kudo
Published in: Journal of gastroenterology (2020)
These findings suggest that the IRF7-IFN-I-IL-33 axis activated in pDCs drives pathogenic innate immune responses associated with type 1 AIP.
Keyphrases
  • dendritic cells
  • immune response
  • regulatory t cells
  • multiple sclerosis
  • transcription factor
  • toll like receptor
  • drug induced
  • inflammatory response