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Efficacy and Safety of Atezolizumab as a PD-L1 Inhibitor in the Treatment of Cervical Cancer: A Systematic Review.

Milan Daniel VelimiroviciCatalin Vladut Ionut FeierRazvan Constantin VonicaAlaviana Monique FaurCalin Muntean
Published in: Biomedicines (2024)
Atezolizumab demonstrates significant potential in improving PFS and OS in patients with cervical cancer, supporting its inclusion as a first-line treatment option. Despite the efficacy benefits, the high incidence of SAEs necessitates careful patient selection and management strategies to mitigate risks. This systematic review supports the continued evaluation of atezolizumab in broader clinical trials to refine its therapeutic profile and safety measures in the context of cervical cancer treatment.
Keyphrases
  • systematic review
  • clinical trial
  • human health
  • meta analyses
  • case report
  • risk factors
  • risk assessment
  • open label
  • climate change
  • phase ii
  • combination therapy
  • phase iii