(-)-Epicatechin induces mitochondrial biogenesis and markers of muscle regeneration in adults with Becker muscular dystrophy.

Craig M McDonaldIsrael Ramirez-SanchezBjörn E OskarssonNanette JoyceCandace AguilarAlina NicoriciJonathan DayanErica GoudeR Ted AbreschFrancisco Villarreal Guillermo CeballosGuy PerkinsSundeep DugarGeorge SchreinerErik K Henricson

Published in: Muscle & nerve (2020)

(-)-Epicatechin, an exercise mimetic, appears to have short-term positive effects on tissue biomarkers indicative of mitochondrial biogenesis and muscle regeneration, and produced improvements in graded exercise testing parameters in patients with BMD.

Keyphrases

muscular dystrophy
stem cells
high intensity
oxidative stress
skeletal muscle
duchenne muscular dystrophy
physical activity
resistance training
wound healing