Strict network analysis of evolutionary conserved and brain-expressed genes reveals new putative candidates implicated in Intellectual Disability and in Global Development Delay.

Rafael Mina Piergiorge Ana Tereza Ribeiro de Vasconcelos Márcia Mattos Gonçalves Pimentel Cintia Barros Santos-Rebouças

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2020)

Our findings expanded the aetiological genetic landscape of ID/GDD and showed evidence that both conditions are closely related at the molecular and functional levels.

Keyphrases

intellectual disability
genome wide
autism spectrum disorder
dna methylation
copy number
white matter
transcription factor
resting state
single molecule
cerebral ischemia
bioinformatics analysis
gene expression
genome wide identification
multiple sclerosis
subarachnoid hemorrhage
network analysis