Can harmful lifestyle, obesity and weight changes increase the risk of breast cancer in BRCA 1 and BRCA 2 mutation carriers? A Mini review.

Antonella DanieleR DivellaB PilatoS TommasiP PasanisiM PatrunoM DigennaroC MinoiaM DellinoS PiscontiP CasamassimaE SavinoA V Paradiso

Published in: Hereditary cancer in clinical practice (2021)

Studies with very large case series have been carried out but only few of them have shown consistent results. Additional research would be beneficial to better determine the actual role and impact of such factors.

Keyphrases

weight loss
breast cancer risk
metabolic syndrome
weight gain
physical activity
insulin resistance
body mass index
type diabetes
cardiovascular disease
high fat diet induced
case control
skeletal muscle
body weight