HIV-coinfected patients respond worse to direct-acting antiviral-based therapy against chronic hepatitis C in real life than HCV-monoinfected individuals: a prospective cohort study.
Karin NeukamLuis E Morano-AmadoAntonio Rivero-JuárezMaría ManceboRafael GranadosFrancisco TéllezAntonio ColladoMaría J RíosIgnacio de Los Santos-GilSergio Reus-BañulsFrancisco Vera-MéndezPaloma Geijo-MartínezMarta Montero-AlonsoMarta Suárez-SantamaríaJuan A PinedaPublished in: HIV clinical trials (2018)
HIV-coinfection is associated with worse response to DAA-based therapy against HCV infection. In patients receiving IFN-free therapy, this fact seems to be mainly driven by a higher rate of relapses among HIV-coinfected subjects.