Associations of Helicobacter pylori and hepatitis A seropositivity with asthma in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): addressing the hygiene hypothesis.

Christian S AlvarezM Larissa Avilés-SantaNeal D FreedmanKrista M PerreiraOlga Garcia-BedoyaRobert C KaplanMartha L DaviglusBarry I GraubardGregory A TalaveraBharat ThyagarajanM Constanza Camargo

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2021)

Our findings did not provide support for the role of H. pylori or HAV, as evidence of the hygiene hypothesis in asthma among the large and diverse Hispanic/Latino populations of the HCHS/SOL. Trial registration NCT02060344.

Keyphrases

helicobacter pylori
chronic obstructive pulmonary disease
african american
clinical trial
lung function
study protocol
cystic fibrosis
open label
genetic diversity