Genome-wide based model predicting recovery from portosystemic shunting after liver shunt attenuation in dogs.

Lindsay Van den BosscheFrank G van SteenbeekMaarten F WeberBart SpeeLouis C PenningFreek J van SluijsFlin ZomerdijkMarian J A Groot KoerkampJan RothuizenIwan A BurgenerAnne Kummeling

Published in: Journal of veterinary internal medicine (2018)

A preclinical model was constructed using preoperative plasma albumin concentration and intraoperative hepatic mRNA expression of 3 genes that were unbiasedly selected from the genome to predict recovery from portosystemic shunting after shunt ligation. Further development is essential for clinical application.

Keyphrases

genome wide
dna methylation
patients undergoing
pulmonary artery
copy number
gene expression
cell therapy
mesenchymal stem cells
transcription factor
bioinformatics analysis