Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage.
Ioannis GallosAdam DevallJames MartinLee MiddletonLeanne BeesonHadiza GaladanciFadhlun Alwy Al-BeityZahida QureshiG Justus HofmeyrNeil MoranSue FawcusLumaan SheikhGeorge GwakoAlfred OsotiAshraf AswatKristie-Marie MammolitiKulandaipalayam N SindhuMarcelina PodesekIsobelle HorneRebecca TimmsIdnan YunasJenipher OkoreMandisa Singata-MadlikiEdna ArendsAminu A WakiliArd MwampashiSidrah NausheenShah MuhammadPallavi LattheCherrie EvansShahinoor AkterGillian ForbesDavid LissauerShireen MeherAndrew WeeksAndrew ShennanAnne AmmerdorfferEleanor WilliamsTracy RobertsMariana WidmerOlufemi T OladapoFabiana LorencattoMeghan A BohrenSuellen MillerFernando AlthabeMetin GülmezogluJeffrey M SmithKarla HemmingArri CoomarasamyPublished in: The New England journal of medicine (2023)
Early detection of postpartum hemorrhage and use of bundled treatment led to a lower risk of the primary outcome, a composite of severe postpartum hemorrhage, laparotomy for bleeding, or death from bleeding, than usual care among patients having vaginal delivery. (Funded by the Bill and Melinda Gates Foundation; E-MOTIVE ClinicalTrials.gov number, NCT04341662.).