Absence of BRAFV600E mutation in odontogenic keratocysts.
Josiane Alves FrançaSílvia Ferreira de SousaMarina Gonçalves DinizThaís Dos Santos Fontes PereiraTaynara Asevedo Campos de ResendeJean Nunes Dos SantosHélder Antônio Rebelo PontesCarolina Cavaliéri GomesPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)
On the basis of our results, OKCs do not present recurrent hotspot mutations in these 50 genes commonly mutated in cancer. In addition, BRAFV600E does not play a central role in OKC pathogenesis.