Targeting the NLRP3 inflammasome for the treatment of hypertensive target organ damage: Role of natural products and formulations.

Xiaolin LiaoYuanshan HanChuanpu ShenJianjun LiuYu-Hong Wang

Published in: Phytotherapy research : PTR (2023)

The NLRP3 inflammasome is a promising therapeutic target in hypertensive TOD. Natural products and formulations that inhibit the NLRP3 inflammasome may provide novel drug candidates or therapies for hypertensive TOD. Further studies are needed to elucidate the molecular mechanisms and optimize the dosages of these natural products and formulations and evaluate their clinical efficacy and safety.

Keyphrases

nlrp inflammasome
blood pressure
cancer therapy
emergency department
case control
drug induced
adverse drug
replacement therapy