Predictive Role of F2-Isoprostanes as Biomarkers for Brain Damage after Neonatal Surgery.
L J StolwijkP M A LemmersM Y A van HerwaardenD C van der ZeeF van BelFloris GroenendaalM L TatarannoM CalderisiM LonginiFrancesco BazziniManon J N L BendersGiuseppe BuonocorePublished in: Disease markers (2017)
Oxidative stress seems to occur during anaesthesia in this cohort of neonates. Plasma nonprotein-bound iron showed to be associated with nonparenchymal injury after surgery, with values of 1.34 umol/L or higher. Risk factors should be elucidated in a more homogeneous patient group.
Keyphrases
- oxidative stress
- risk factors
- minimally invasive
- coronary artery bypass
- resting state
- case report
- white matter
- diabetic rats
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- low birth weight
- functional connectivity
- surgical site infection
- cerebral ischemia
- signaling pathway
- acute coronary syndrome
- heat shock
- blood brain barrier